Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885683 | 0.86 | CFTR (0.54) | CFTRHTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7678317 | 0.85 | KMT2A (0.43) | CFTRENPP2PKMHTTALDH1A1 | |
| SCHEMBL7676293 | 0.83 | CETP (0.38) | ENPP2PKMHTTSMN1; SMN2KMT2A | |
| SCHEMBL7687627 | 0.83 | HTT (0.39) | HTTALDH1A1SMN1; SMN2KMT2AMAOB | |
| SCHEMBL1258016 | 0.78 | MAPT (0.43) | ENPP2PKMHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7678488 | 0.78 | HTT (0.41) | HTTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8097559 | 0.74 | ACACB (0.41) | CFTRHTTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8873939 | 0.74 | ACACB (0.41) | CFTRHTTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8872841 | 0.74 | ACACB (0.40) | HTTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8873931 | 0.74 | HTT (0.39) | HTTALDH1A1SMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362206-B1 | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-6034248-A | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-07 | — | — | US | disclosed |