Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | FABP6 | P51161 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675250 | 0.79 | HTR2C (0.51) | HTR2COPRM1AKT1KMT2A | |
| SCHEMBL11244523 | 0.76 | MAPT (0.47) | HTR2CAKR1B1MAPTAKR1B10AKR1A1 | |
| Hydrochloric Acid SCHEMBL11242648 | 0.75 | MAPT (0.47) | HTR2CAKR1B1MAPTAKR1B10AKR1A1 | |
| SCHEMBL3381491 | 0.74 | OPRM1 (0.50) | HTR2COPRM1 | |
| SCHEMBL29836006 | 0.74 | AKR1B1 (0.43) | AKR1B1MAPTAKR1B10AKR1A1FABP6 | |
| SCHEMBL3742950 | 0.73 | HTR2C (0.46) | HTR2CAKR1B1MAPTAKR1B10AKR1A1 | |
| SCHEMBL7675502 | 0.73 | PDK2 (0.47) | HTR2CAKR1B1AKR1A1OPRM1NR3C2 | |
| SCHEMBL7675510 | 0.73 | HTR2C (0.46) | HTR2COPRM1KMT2A | |
| Hydrochloric Acid SCHEMBL11389522 | 0.73 | OPRM1 (0.48) | HTR2COPRM1 | |
| Hydrochloric Acid SCHEMBL2800247 | 0.72 | HTR2C (0.44) | HTR2CAKR1B1MAPTAKR1B10AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387893-B1 | ADRENERGIC BLOCKING AGENT; BENIGN PROSATATIC HYPERPLASIA | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |