Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18235578 | 0.89 | SMN1; SMN2 (0.59) | ALDH1A1HPGDHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL1204120 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL5657977 | 0.83 | MEN1 (0.58) | ALDH1A1HPGDHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL2546081 | 0.83 | ALDH1A1 (0.68) | ALDH1A1HPGDHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL30223440 | 0.83 | ALDH1A1 (0.68) | ALDH1A1HPGDHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL5657924 | 0.82 | HPGD (0.62) | ALDH1A1HPGDSMN1; SMN2MAPK1HDAC3 | |
| SCHEMBL13162943 | 0.82 | NPC1 (0.59) | ALDH1A1HPGDSMN1; SMN2MAPK1KDM4E | |
| SCHEMBL13299189 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1HPGDHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL5655209 | 0.82 | NPC1 (0.65) | HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5657148 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1HPGDSMN1; SMN2MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407116-B1 | 2,4-DIOXO-1,2,3,4-TETRAHYDROQUINAZOLINE DERIVATIVES; ANTIALLERGENS, ANTIASTHMATICS, ANTIHISTAMINES, AND ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1026160-A1 | NITROGENOUS FUSED-RING COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME, AND DRUGS | Takeda Chemical Industries, Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |