Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18235578 | 0.89 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10310896 | 0.89 | MT-CO2 (0.58) | PTGS2MT-CO2MAPK1LMNACYP1A2 | |
| SCHEMBL10310894 | 0.87 | MT-CO2 (0.60) | PTGS2HPGDMT-CO2LMNACYP1A2 | |
| SCHEMBL5657977 | 0.83 | MEN1 (0.58) | SMN1; SMN2ALDH1A1GAAKDM4EHSD17B10 | |
| SCHEMBL7678490 | 0.82 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL5657148 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1GAAHPGDTSHR | |
| SCHEMBL5657924 | 0.82 | HPGD (0.62) | SMN1; SMN2ALDH1A1GAAHPGDTSHR | |
| SCHEMBL31661799 | 0.82 | HPGD (0.62) | SMN1; SMN2ALDH1A1GAAHPGDTSHR | |
| SCHEMBL5655209 | 0.82 | NPC1 (0.65) | SMN1; SMN2HPGDCYP1A2NPC1RAB9A | |
| SCHEMBL13162943 | 0.82 | NPC1 (0.59) | SMN1; SMN2ALDH1A1KDM4EHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403756-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-02 | — | — | US | disclosed |
| US-9403756-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-02 | — | — | US | disclosed |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-10-23 | — | — | US | disclosed |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-10-23 | — | — | US | disclosed |
| US-8765815-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-07-01 | — | — | US | disclosed |
| US-8765815-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-07-01 | — | — | US | disclosed |
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-03 | — | — | US | disclosed |
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-03 | — | — | US | disclosed |
| WO-2009037707-A2 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2009-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | TRPV1, TRPA1, TRPV4 | SMN1; SMN2 1120/4885PTGS2 1097/4885PKM 354/4885 |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | TRPV1, TRPA1, TRPV4 | SMN1; SMN2 1120/4885PTGS2 1097/4885PKM 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.