SCHEMBL7678596

SCHEMBL7678596

O=C(Nc1ccccc1NC(=O)c1ccccc1O)c1ccccc1O

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.88
HTT P42858 5/20 0.88
NPC1 O15118 5/20 0.88
TP53 P04637 4/20 0.88
GAA P10253 2/20 0.88
HSD17B10 Q99714 5/20 0.76
KDM4E B2RXH2 3/20 0.76
HPGD P15428 3/20 0.76
ALDH1A1 P00352 1/20 0.76
MAPK1 P28482 1/20 0.76
RAB9A P51151 5/20 0.69
TSHR P16473 2/20 0.69
MEN1 O00255 4/20 0.68
KMT2A Q03164 4/20 0.68
KCNMA1 Q12791 4/20 0.67
SMN1; SMN2 Q16637 3/20 0.63
MPO P05164 1/20 0.63
HIF1A Q16665 1/20 0.63
METAP2 P50579 1/20 0.62
NFKB1 P19838 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL845142 0.94 LMNA (1.00) LMNAHTTNPC1TP53GAA
SCHEMBL28842439 0.92 LMNA (0.96) LMNAHTTNPC1TP53GAA
SCHEMBL28842312 0.92 LMNA (0.96) LMNAHTTNPC1TP53GAA
SCHEMBL2701324 0.88 HTT (0.76) LMNAHTTNPC1TP53GAA
SCHEMBL4669122 0.88 LMNA (0.76) LMNAHTTNPC1TP53GAA
SCHEMBL11405554 0.88 LMNA (0.76) LMNAHTTNPC1TP53GAA
SCHEMBL2699674 0.87 LMNA (0.73) LMNAHTTNPC1TP53GAA
SCHEMBL27516656 0.87 LMNA (0.73) LMNAHTTNPC1TP53GAA
SCHEMBL5079194 0.87 LMNA (1.00) LMNAHTTNPC1TP53GAA
SCHEMBL2701801 0.87 HPGD (0.77) LMNAHTTNPC1TP53GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9896465-B2 Phosphonium compound, preparation method thereof, epoxy resin composition including the same, and semiconductor device prepared by using the same SAMSUNG SDI CO., LTD. (KR) 2018-02-20 US disclosed
US-20160368937-A1 PHOSPHONIUM COMPOUND, PREPARATION METHOD THEREOF, EPOXY RESIN COMPOSITION INCLUDING THE SAME, AND SEMICONDUCTOR DEVICE PREPARED BY USING THE SAME SAMSUNG SDI CO., LTD. (KP) 2016-12-22 US disclosed
US-6395904-B1 HYDROXYAMIDE COMPLEXES WITH IRON YALE UNIVERSITY 2002-05-28 US disclosed
US-4758682-A Homogeneous coordination compounds as oxidation catalysts CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1988-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160368937-A1 PHOSPHONIUM COMPOUND, PREPARATION METHOD THEREOF, EPOXY RESIN COMPOSITION INCLUDING THE SAME, AND SEMICONDUCTOR DEVICE PREPARED BY USING THE SAME PHOSPHO1, PPA1, ASH2L LMNA 4549/4885HTT 4217/4885NPC1 3927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.