SCHEMBL845142

SCHEMBL845142

O=C(Nc1ccccc1O)c1ccccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 1.00
HTT P42858 5/20 1.00
TP53 P04637 5/20 1.00
NPC1 O15118 5/20 1.00
GAA P10253 3/20 1.00
HSD17B10 Q99714 5/20 0.73
KDM4E B2RXH2 3/20 0.73
HPGD P15428 2/20 0.73
MAPK1 P28482 2/20 0.73
ALDH1A1 P00352 1/20 0.73
METAP2 P50579 1/20 0.71
RAB9A P51151 5/20 0.67
KCNMA1 Q12791 4/20 0.67
TSHR P16473 2/20 0.67
MEN1 O00255 4/20 0.66
KMT2A Q03164 4/20 0.66
MAPT P10636 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
MPO P05164 1/20 0.61
HIF1A Q16665 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28842439 0.98 LMNA (0.96) LMNAHTTTP53NPC1GAA
SCHEMBL28842312 0.98 LMNA (0.96) LMNAHTTTP53NPC1GAA
SCHEMBL7678596 0.94 LMNA (0.88) LMNAHTTTP53NPC1GAA
SCHEMBL926677 0.86 NPC1 (0.76) LMNAHTTTP53NPC1GAA
SCHEMBL4669122 0.86 LMNA (0.76) LMNAHTTTP53NPC1GAA
SCHEMBL28965115 0.86 LMNA (0.76) LMNAHTTTP53NPC1GAA
SCHEMBL11405554 0.86 LMNA (0.76) LMNAHTTTP53NPC1GAA
SCHEMBL4930820 0.86 NPC1 (0.76) LMNAHTTTP53NPC1GAA
SCHEMBL2701324 0.86 HTT (0.76) LMNAHTTTP53NPC1GAA
SCHEMBL2699674 0.85 LMNA (0.73) LMNAHTTTP53NPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112724037-B Hydroxyl benzene salicylamine hydroxylate, preparation method and application thereof 浙江大学 2022-03-11 CN claimed
CN-112724037-A Hydroxyl benzene salicylamine hydroxylate, preparation method and application thereof 浙江大学 2021-04-30 CN claimed
EP-0670855-A1 NITRO OR NITROSO GROUP TERMINATED MESOGENIC EPOXY RESIN ADDUCTS THE DOW CHEMICAL COMPANY (US) 1995-09-13 EP claimed
WO-1994012555-A1 NITRO OR NITROSO GROUP TERMINATED MESOGENIC EPOXY RESIN ADDUCTS THE DOW CHEMICAL COMPANY (US) 1994-06-09 WO claimed
EP-0379059-A1 Dihydroxybenzophenone oximes, their preparation and rearrangement to the anilide THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP claimed
JP-2270849-A None JP disclosed
US-20250320347-A1 ADHESION-PROMOTING SYSTEM FOR A RUBBER COMPOSITION ALLNEX GERMANY GMBH (DE) 2025-10-16 US disclosed
EP-4526377-A1 ADHESION-PROMOTING SYSTEM FOR A RUBBER COMPOSITION Allnex Germany GmbH (DE) 2025-03-26 EP disclosed
CN-113637154-B Nonionic polyether type high-molecular surfactant and preparation method and application thereof 常熟耐素生物材料科技有限公司 2025-03-11 CN disclosed
CN-119156418-A Adhesion promoting system for rubber compositions 湛新德国有限公司 2024-12-17 CN disclosed
WO-2023222427-A1 ADHESION-PROMOTING SYSTEM FOR A RUBBER COMPOSITION ALLNEX GERMANY GMBH (DE) 2023-11-23 WO disclosed
EP-4279540-A1 ADHESION-PROMOTING SYSTEM FOR A RUBBER COMPOSITION ALLNEX GERMANY GmbH (DE) 2023-11-22 EP disclosed
EP-0379057-A2 Mesogenic epoxy compounds THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP disclosed
EP-0379059-A1 Dihydroxybenzophenone oximes, their preparation and rearrangement to the anilide THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP disclosed
EP-0091519-B1 TOPICAL ACYLAMINOPHENOLS Johnson & Johnson Products Inc. (US) 1987-06-24 EP disclosed
US-4581996-A Aluminum support useful for lithography AMERICAN HOECHST CORPORATION (US) 1986-04-15 US disclosed
US-4427500-A Method for producing an aluminum support useful for lithography AMERICAN HOECHST CORPORATION (US) 1984-01-24 US disclosed
EP-0091519-A1 Topical acylaminophenols Johnson & Johnson Products Inc. (US) 1983-10-19 EP disclosed
US-4329366-A ANTIINFLAMMATORY AGENTS JOHNSON & JOHNSON PRODUCTS, INC. (US) 1982-05-11 US disclosed
US-4216076-A POLYALKYLENEOXY SULFOXY SALT NL INDUSTRIES, INC. (US) 1980-08-05 US disclosed