Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | CTSB | P07858 | 3/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650290 | 0.92 | KLK5 (0.50) | TACR1PPARAACECTSSCTSK | |
| SCHEMBL7673164 | 0.88 | CTSS (0.51) | TACR1ACECTSSCTSKCTSB | |
| SCHEMBL27406840 | 0.87 | TACR1 (0.54) | TACR1PPARAACECTSSCTSK | |
| SCHEMBL6572493 | 0.87 | PPARA (0.54) | TACR1PPARAACECTSSCTSK | |
| SCHEMBL9888267 | 0.87 | PPARA (0.54) | TACR1PPARAACECTSSCTSK | |
| SCHEMBL7676458 | 0.86 | PTPN1 (0.52) | TACR1PPARAACECTSSCTSK | |
| SCHEMBL4650885 | 0.84 | PPARA (0.51) | TACR1PPARAACECTSSCTSK | |
| SCHEMBL7047080 | 0.84 | PPARA (0.51) | TACR1PPARAACECTSSCTSK | |
| SCHEMBL7164557 | 0.84 | PPARA (0.51) | TACR1PPARAACECTSSCTSK | |
| SCHEMBL5375331 | 0.83 | TACR1 (0.53) | TACR1PPARAACECTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |
| EP-1161421-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | Pharmacia & Upjohn Aktiebolag (SE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000053583-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2000-09-14 | — | — | WO | disclosed |