Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679500 | 0.90 | CDK2 (0.43) | CDK2CDK4 | |
| SCHEMBL7676606 | 0.89 | CDK2 (0.43) | CDK2KMT2ACDK4MAPTPIN1 | |
| SCHEMBL7674349 | 0.89 | TRPV1 (0.40) | SRD5A2CDK2ADORA3CDK4 | |
| SCHEMBL7680224 | 0.89 | ATM (0.42) | CDK2NPC1RAB9AADORA3CDK4 | |
| SCHEMBL7680009 | 0.86 | CDK2 (0.39) | CDK2NPC1RAB9ACDK4 | |
| SCHEMBL7676480 | 0.86 | NAMPT (0.39) | CDK2CDK4 | |
| SCHEMBL7673714 | 0.86 | LRRK2 (0.37) | CNR2LRRK2KMT2AMEN1NPC1 | |
| SCHEMBL7679621 | 0.85 | CDK2 (0.43) | CDK2KMT2ACDK4MAPTCYP2C9 | |
| SCHEMBL7676353 | 0.85 | CDK2 (0.42) | CNR2CDK2KMT2ACDK4 | |
| SCHEMBL7680020 | 0.85 | CDK2 (0.41) | LRRK2SRD5A2CDK2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |