Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679500 | 0.93 | CDK2 (0.43) | CDK2USP7CDK4 | |
| SCHEMBL7682045 | 0.91 | CDK2 (0.43) | CDK2USP7CDK4 | |
| SCHEMBL7680034 | 0.90 | CDK2 (0.40) | CDK2USP7CDK4 | |
| SCHEMBL7677596 | 0.90 | CDK2 (0.41) | CDK2USP7ADORA3CDK4 | |
| SCHEMBL7678672 | 0.89 | CNR2 (0.45) | CDK2ADORA3CDK4SRD5A2 | |
| SCHEMBL7675092 | 0.88 | AKT1 (0.47) | CDK2USP7CDK4 | |
| SCHEMBL7673955 | 0.87 | NPC1 (0.42) | CDK2USP7ADORA3 | |
| SCHEMBL7680199 | 0.87 | TLR7 (0.39) | MCHR1CDK2USP7CDK4 | |
| SCHEMBL7680009 | 0.87 | CDK2 (0.39) | CDK2USP7CDK4 | |
| SCHEMBL7676765 | 0.86 | POLB (0.46) | CDK2CDK4SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |