Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 6/20 | 0.52 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL406740 | 0.86 | CDC7 (0.54) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL1586157 | 0.82 | CDC7 (0.46) | CDC7DBF4MEN1KMT2ANPC1 | |
| SCHEMBL8823153 | 0.81 | ALDH1A1 (0.75) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL24508628 | 0.79 | JAK2 (0.51) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL1340065 | 0.78 | TRPM8 (0.62) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL1340195 | 0.77 | TRPM8 (0.65) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL10242415 | 0.76 | NPC1 (0.50) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL953635 | 0.76 | CDC7 (0.47) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL6766164 | 0.75 | DHODH (0.60) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL1968834 | 0.75 | TRPM8 (0.60) | CDC7DBF4ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413997-B1 | INSECTICIDES, MITICIDES | DOW AGROSCIENCES LLC | 2002-07-02 | — | — | US | disclosed |
| EP-1124827-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | Dow AgroSciences LLC (US) | 2001-08-22 | — | — | EP | disclosed |
| US-6096898-A | One pot synthesis of 1,2,4-triazoles | DOW AGROSCIENCES LLC (US) | 2000-08-01 | — | — | US | disclosed |
| WO-2000024739-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |