SCHEMBL7679043

SCHEMBL7679043

NC(=O)Cc1ccccc1Oc1ccccn1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC1A5 Q15758 2/20 0.54
KDM4E B2RXH2 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
P2RX4 Q99571 1/20 0.44
CXCL8 P10145 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
SCN7A Q01118 1/20 0.39
KCNH2 Q12809 1/20 0.39
ALDH1A1 P00352 2/20 0.39
PLA2G10 O15496 1/20 0.38
P2RX7 Q99572 1/20 0.38
HTT P42858 1/20 0.37
CHRM1 P11229 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4611564 0.86 CXCL8 (0.56) SLC1A5KDM4ETDP1P2RX4CXCL8
SCHEMBL9732533 0.80 KDM4E (0.51) SLC1A5KDM4EL3MBTL1PDE4APDE4B
SCHEMBL8486800 0.80 NPC1 (0.41) SLC1A5KDM4ETDP1ALDH1A1PLA2G10
SCHEMBL8287033 0.79 KDM4E (0.51) SLC1A5KDM4EP2RX4P2RX7
SCHEMBL6827514 0.79 KDM4E (0.51) SLC1A5KDM4EP2RX4PDE4APDE4B
SCHEMBL5023935 0.79 KDM4E (0.51) SLC1A5KDM4EL3MBTL1PDE4APDE4B
Hydrochloric Acid SCHEMBL3291564 0.78 KDM4E (0.50) SLC1A5KDM4EP2RX4P2RX7
SCHEMBL7428731 0.76 CTNNB1 (0.57) SLC1A5KDM4EALDH1A1HTT
SCHEMBL31414009 0.76 CTNNB1 (0.57) SLC1A5KDM4EALDH1A1HTT
SCHEMBL8777954 0.76 KDM4E (0.51) SLC1A5KDM4EP2RX4PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372766-B1 FUNGICIDES AND ANTIGROWTH AGENTS BASF AKTIENGESELLSCHAFT (DE) 2002-04-16 US claimed
US-6372766-B1 FUNGICIDES AND ANTIGROWTH AGENTS BASF AKTIENGESELLSCHAFT (DE) 2002-04-16 US disclosed
US-6372766-B1 FUNGICIDES AND ANTIGROWTH AGENTS BASF AKTIENGESELLSCHAFT (DE) 2002-04-16 US disclosed
EP-1027334-A1 SUBSTITUTED 2-(2'-PYRIDYLOXY)PHENYL ACETAMIDES AS FUNGICIDES AND PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-08-16 EP disclosed
WO-1999021833-A1 SUBSTITUTED 2-(2'-PYRIDYLOXY)PHENYL ACETAMIDES AS FUNGICIDES AND PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-05-06 WO disclosed