Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 1.00 |
| ▸ | CA9 | Q16790 | 3/20 | 1.00 |
| ▸ | CA1 | P00915 | 2/20 | 1.00 |
| ▸ | CA4 | P22748 | 2/20 | 1.00 |
| ▸ | CA5A | P35218 | 2/20 | 1.00 |
| ▸ | CA7 | P43166 | 2/20 | 1.00 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 1.00 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 1.00 |
| ▸ | CA2 | P00918 | 1/20 | 1.00 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.59 |
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928220 | 0.89 | CA12 (0.81) | CA12CA9CA1CA4CA5A | |
| Hydrochloric Acid SCHEMBL7931072 | 0.88 | CA12 (0.78) | CA12CA9CA1CA4CA5A | |
| SCHEMBL1366682 | 0.87 | CA12 (0.77) | CA12CA9CA1CA4CA5A | |
| SCHEMBL2292433 | 0.84 | CA2 (0.72) | CA12CA9CA1CA4CA5A | |
| SCHEMBL7922159 | 0.77 | CA2 (0.63) | CA12CA9CA1CA4CA5A | |
| SCHEMBL1368083 | 0.76 | CA12 (0.60) | CA12CA9CA1CA4CA5A | |
| SCHEMBL7681070 | 0.76 | CA12 (0.60) | CA12CA9CA1CA4CA5A | |
| SCHEMBL15025442 | 0.75 | CA1 (0.60) | CA12CA9CA1CA4CA5A | |
| SCHEMBL93858 | 0.75 | BCL2L1 (1.00) | CA12CA9CA1CA4CA5A | |
| SCHEMBL1538456 | 0.75 | CA2 (0.59) | CA12CA9CA1CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |
| EP-0988298-A1 | COUMARIN DERIVATIVES, METHODS OF PREPARATION AND APPLICATION AS MEDICINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998055472-A1 | COUMARIN DERIVATIVES, METHODS OF PREPARATION AND APPLICATION AS MEDICINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-12-10 | — | — | WO | disclosed |