Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PLEC | Q15149 | 1/20 | 0.37 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673483 | 0.84 | ALDH1A1 (0.50) | KMT2APTGER4ALDH1A1MAPTKDM4E | |
| SCHEMBL6779617 | 0.81 | SMN1; SMN2 (0.50) | PRKCIMEN1KMT2AGAAPTGER4 | |
| SCHEMBL506325 | 0.75 | PRKCI (0.46) | PRKCIMEN1KMT2AGAAPTGER4 | |
| SCHEMBL28798220 | 0.74 | ADRA2C (0.47) | PRKCIMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL6776686 | 0.73 | GAA (0.44) | PRKCIMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL6782253 | 0.72 | MAPT (0.51) | MEN1KMT2AGAAPTGER4ALDH1A1 | |
| SCHEMBL29276650 | 0.71 | KMT2A (0.41) | PRKCIKMT2AGAAPTGER4ALDH1A1 | |
| SCHEMBL6779269 | 0.71 | ADRA2C (0.41) | PRKCIMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL408918 | 0.71 | PTGER4 (0.67) | PRKCIKMT2AGAAPTGER4ALDH1A1 | |
| SCHEMBL29276987 | 0.70 | PRKCI (0.40) | PRKCIMEN1KMT2AGAAPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469039-B1 | BENZIMIDAZOLES; THROMBIN- INHIBITING ACTIVITY AND THE EFFECT OF EXTENDING THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-10-22 | — | — | US | disclosed |
| US-6087380-A | ANTITHROMBOTIC BENZIMIDAZOLES; ANTICOAGULANTS; 2-(N-(4-AMIDINOPHENYL)-AMINOMETHYL)-BENZIMIDAZOL-5-YL-CARBOXYLIC ACIDS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-07-11 | — | — | US | disclosed |