Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 9/20 | 0.37 |
| ▸ | EDNRA | P25101 | 7/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211196 | 0.76 | EDNRB (0.56) | EDNRBEDNRA | |
| SCHEMBL7205015 | 0.73 | EDNRB (0.54) | EDNRBEDNRA | |
| SCHEMBL6289257 | 0.68 | ALDH1A1 (0.35) | EDNRASLC6A9MEN1KMT2A | |
| SCHEMBL26143739 | 0.68 | EDNRA (0.43) | EDNRBEDNRA | |
| SCHEMBL26143794 | 0.67 | ALOX5 (0.41) | EDNRBEDNRA | |
| SCHEMBL6288973 | 0.66 | EDNRB (0.53) | EDNRBEDNRA | |
| SCHEMBL22504840 | 0.66 | EDNRA (0.44) | EDNRBEDNRA | |
| SCHEMBL22404243 | 0.66 | EDNRA (0.72) | EDNRBEDNRA | |
| SCHEMBL7317941 | 0.66 | EDNRB (0.45) | EDNRB | |
| SCHEMBL7318413 | 0.66 | EDNRB (0.45) | EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387915-B2 | VASODILATION | PFIZER INC. | 2002-05-14 | — | — | US | disclosed |