Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 11/20 | 0.53 |
| ▸ | HTR3A | P46098 | 11/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HRH2 | P25021 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29475022 | 1.00 | HAO1 (0.55) | HAO1HTR1AHTR3ALMNATP53 | |
| SCHEMBL13057071 | 0.89 | HTR1A (0.57) | HAO1HTR1AHTR3ALMNATP53 | |
| SCHEMBL3538549 | 0.87 | HAO1 (0.46) | HAO1HTR1AHTR3ALMNATP53 | |
| SCHEMBL14252178 | 0.85 | HAO1 (0.49) | HAO1HTR1AHTR3ALMNATP53 | |
| SCHEMBL576257 | 0.83 | NPC1 (0.50) | HAO1HTR1AHTR3ALMNATP53 | |
| SCHEMBL29411684 | 0.83 | NPC1 (0.50) | HAO1HTR1AHTR3ALMNATP53 | |
| SCHEMBL11225501 | 0.82 | HTR1A (0.59) | HAO1HTR1AHTR3ALMNATP53 | |
| SCHEMBL7674839 | 0.82 | HTR1A (0.50) | HAO1HTR1AHTR3ALMNAHPGD | |
| SCHEMBL14723181 | 0.82 | SLC6A4 (0.57) | HTR1AHTR3AMEN1MAPTKMT2A | |
| SCHEMBL3546034 | 0.82 | HAO1 (0.42) | HAO1HTR1AHTR3ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015079018-A1 | SYNTHESIS OF VORTIOXETINE VIA (2-(PIPERAZINE-1 -YL)PHENVL)LITHIUM INTERMEDIATES | LEK PHARMACEUTICALS D.D. (SI) | 2015-06-04 | — | — | WO | claimed |
| EP-2878596-A1 | Synthesis of vortioxetine via (2-(piperazine-1-yl)phenyl)lithium intermediates | LEK Pharmaceuticals d.d. (SI) | 2015-06-03 | — | — | EP | claimed |
| US-4210766-A | BROMINATION OF 2-HALOPHENOLS | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | claimed |
| US-12100809-B2 | Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-09-24 | — | — | US | disclosed |
| CN-112533934-B | Polyoxometallate compounds exhibiting bright emissions and methods of making same | 纳米2D材料有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-118084824-A | Synthesis method of antidepressant drug, namely voethidine | 万特制药(海南)有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117924215-A | Synthesis method of vothixetine | 万全万特制药（厦门）有限公司 | 2024-04-26 | — | — | CN | disclosed |
| EP-3383503-B1 | HYDROGEN PEROXIDE BOOSTER SYSTEM FOR ENHANCED TEETH WHITENING | COLGATE PALMOLIVE CO (US) | 2022-07-27 | — | — | EP | disclosed |
| CN-114656363-A | Synthetic method of palladium-catalyzed aromatic ester compound | 南京林业大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-108603177-B | Enzyme delivery system | 纳幕尔杜邦公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-108778688-B | Radiation curable compositions for additive fabrication having improved toughness and high temperature resistance | 科思创(荷兰)有限公司 | 2022-05-13 | — | — | CN | disclosed |
| US-6417374-B1 | Process for the preparation of beta hydroxy-delta lactone using novel intermediates | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2002-07-09 | — | — | US | disclosed |
| WO-2001007386-A2 | ASYMMETRIC LIGANDS HAVING USE AS CATALYSTS | 1428388 ONTARIO LIMITED (CA) | 2001-02-01 | — | — | WO | disclosed |
| US-5912212-A | OIL WITH 3-METHYL-5-TERT-BUTYL-4-HYDROXYPHENYL FATTY ESTER, SULFUR AND PHOSPHORUS | NIPPON OIL CO., LTD. (JP) | 1999-06-15 | — | — | US | disclosed |
| EP-0795023-A1 | A PROCESS FOR PRODUCING SULPHOXIDE ENRICHED IN THE (R) OR THE (S) ENANTIOMER | ZENECA LIMITED (GB) | 1997-09-17 | — | — | EP | disclosed |
| EP-0781834-A2 | Lubricating oil composition | NIPPON OIL CO. LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996017075-A1 | A PROCESS FOR PRODUCING SULPHOXIDE ENRICHED IN THE (R) OR THE (S) ENANTIOMER | ZENECA LIMITED (GB) | 1996-06-06 | — | — | WO | disclosed |
| US-4837301-A | FROM ALKALI MTEAL SULFIDES AND AROMATIC DIHALOGEN COMPOUNDS; IMPROVED CORROSION RESISTANCE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-06 | — | — | US | disclosed |
| US-4343029-A | CAPACITORS; TRANSFORMERS | THE DOW CHEMICAL COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4210766-A | BROMINATION OF 2-HALOPHENOLS | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |