Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.59 |
| ▸ | HTR3A | P46098 | 11/20 | 0.59 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HTR5A | P47898 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14252178 | 0.87 | HAO1 (0.49) | HTR1AHTR3AHAO1CYP1A2ADRB2 | |
| SCHEMBL13057071 | 0.85 | HTR1A (0.57) | HTR1AHTR3AHAO1CYP1A2ADRB2 | |
| SCHEMBL9488946 | 0.85 | HTR1A (0.45) | HTR1AHTR3ACYP1A2CYP2A6LMNA | |
| SCHEMBL29475022 | 0.82 | HAO1 (0.55) | HTR1AHTR3AHAO1CYP1A2ADRB2 | |
| SCHEMBL76793 | 0.82 | HAO1 (0.55) | HTR1AHTR3AHAO1CYP1A2ADRB2 | |
| SCHEMBL28098549 | 0.82 | HTR1A (0.47) | HTR1AHTR3AHAO1CYP1A2ADRB2 | |
| SCHEMBL9488226 | 0.80 | HAO1 (0.47) | HTR1AHTR3AHAO1CYP1A2CYP2A6 | |
| SCHEMBL14163150 | 0.78 | RAPGEF4 (0.41) | HTR1AHTR3ACYP1A2CYP2A6ACHE | |
| SCHEMBL9487758 | 0.78 | HTR1A (0.40) | HTR1AHTR3ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3541659 | 0.77 | HTR1A (0.44) | HTR1AHTR3AHAO1CYP1A2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343029-A | CAPACITORS; TRANSFORMERS | THE DOW CHEMICAL COMPANY (US) | 1982-08-03 | — | — | US | disclosed |