Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.79 |
| ▸ | CA2 | P00918 | 2/20 | 0.79 |
| ▸ | CA3 | P07451 | 2/20 | 0.79 |
| ▸ | CA6 | P23280 | 2/20 | 0.79 |
| ▸ | CA7 | P43166 | 2/20 | 0.79 |
| ▸ | CA9 | Q16790 | 2/20 | 0.79 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.79 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.79 |
| ▸ | CA4 | P22748 | 1/20 | 0.79 |
| ▸ | MAOB | P27338 | 2/20 | 0.70 |
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | F2 | P00734 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.60 |
| ▸ | MIF | P14174 | 1/20 | 0.60 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.60 |
| ▸ | F12 | P00748 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18752370 | 0.91 | CA12 (0.85) | CA12CA2CA3CA6CA7 | |
| SCHEMBL7678492 | 0.88 | CA12 (1.00) | CA12CA2CA3CA6CA7 | |
| SCHEMBL7696966 | 0.87 | CA12 (0.61) | CA12CA2CA3CA6CA7 | |
| SCHEMBL14642320 | 0.87 | CA12 (0.78) | CA12CA2CA3CA6CA7 | |
| Hydrochloric Acid SCHEMBL7673583 | 0.86 | CA12 (0.77) | CA12CA2CA3CA6CA7 | |
| SCHEMBL14642322 | 0.86 | CA12 (0.77) | CA12CA2CA3CA6CA7 | |
| SCHEMBL11484361 | 0.84 | MAOB (0.74) | CA12CA2CA3CA6CA7 | |
| SCHEMBL27701220 | 0.84 | CA12 (0.74) | CA12CA2CA3CA6CA7 | |
| SCHEMBL5619744 | 0.84 | CA12 (0.55) | CA12CA2CA3CA6CA7 | |
| SCHEMBL30595106 | 0.84 | MAOB (0.78) | CA12CA2CA3CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9814696-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2017-11-14 | — | — | US | disclosed |
| US-9814696-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2017-11-14 | — | — | US | disclosed |
| EP-2731604-B1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIV PIERRE ET MARIE CURIE PARIS 6 (FR) | 2017-04-19 | — | — | EP | disclosed |
| US-20170065555-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2017-03-09 | — | — | US | disclosed |
| US-20170065555-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2017-03-09 | — | — | US | disclosed |
| US-9532973-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2017-01-03 | — | — | US | disclosed |
| US-20150182499-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2015-07-02 | — | — | US | disclosed |
| US-20150182499-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2015-07-02 | — | — | US | disclosed |
| US-9006466-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2015-04-14 | — | — | US | disclosed |
| US-9006466-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2015-04-14 | — | — | US | disclosed |
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2014-05-29 | — | — | US | disclosed |
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2014-05-29 | — | — | US | disclosed |
| WO-2013010963-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2013-01-24 | — | — | WO | disclosed |
| EP-2545916-A1 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | Universite Pierre Et Marie Curie - Paris 6 (FR) | 2013-01-16 | — | — | EP | disclosed |
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | BDKRB1, KLK1, SERPINC1 | CA12 1833/4885CA2 1907/4885CA3 2248/4885 |
| US-20150182499-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | BDKRB1, SERPINC1, KLK1 | CA12 1833/4885CA2 1935/4885CA3 2274/4885 |
| US-20170065555-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | BDKRB1, SERPINC1, KLK1 | CA12 1833/4885CA2 1935/4885CA3 2274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.