Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA3 | P07451 | 2/20 | 0.61 |
| ▸ | CA6 | P23280 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | F12 | P00748 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7702729 | 0.88 | CA12 (0.60) | CA12CA2CA3CA6CA7 | |
| SCHEMBL7679378 | 0.87 | CA12 (0.79) | CA12CA2CA3CA6CA7 | |
| SCHEMBL14134648 | 0.82 | ALDH1A1 (0.83) | CA12CA9KDM4EALDH1A1MAOB | |
| SCHEMBL14642320 | 0.82 | CA12 (0.78) | CA12CA2CA3CA6CA7 | |
| SCHEMBL30992321 | 0.81 | ALDH1A1 (0.81) | CA12CA9KDM4EALDH1A1MAOB | |
| SCHEMBL4905483 | 0.78 | KDM4E (0.85) | CA12CA9KDM4EALDH1A1MAOB | |
| SCHEMBL18752370 | 0.78 | CA12 (0.85) | CA12CA2CA3CA6CA7 | |
| SCHEMBL14652728 | 0.78 | MAOB (0.67) | CA12CA2CA3CA6CA7 | |
| SCHEMBL12611497 | 0.77 | MAOB (0.64) | CA12CA2CA3CA6CA7 | |
| SCHEMBL592309 | 0.77 | MIF (0.73) | CA12CA2CA3CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |