Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 16/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683787 | 0.93 | CASP3 (0.47) | CASP3CASP1 | |
| SCHEMBL7683824 | 0.92 | CASP3 (0.47) | CASP3CASP1 | |
| SCHEMBL7680168 | 0.92 | CASP1 (0.51) | CASP3CASP1 | |
| SCHEMBL7679831 | 0.90 | CASP1 (0.47) | CASP3CASP1 | |
| SCHEMBL7684413 | 0.90 | CASP1 (0.43) | CASP3CASP1 | |
| SCHEMBL7682136 | 0.88 | CASP1 (0.48) | CASP3CASP1 | |
| SCHEMBL8164646 | 0.88 | CASP1 (0.51) | CASP3CASP1 | |
| SCHEMBL7682431 | 0.87 | CASP1 (0.47) | CASP3CASP1 | |
| SCHEMBL7680995 | 0.86 | CASP1 (0.53) | CASP3CASP1 | |
| SCHEMBL7687190 | 0.86 | CASP1 (0.47) | CASP3CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | claimed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | claimed |
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |