SCHEMBL7679547

SCHEMBL7679547

CCOCn1nncc1C=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.31
MAPK14 Q16539 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16051192 0.82 PTGS2 (0.30) PTGS2
SCHEMBL7820707 0.71
SCHEMBL264093 0.65
SCHEMBL17769185 0.64 TOP2A (0.35)
SCHEMBL3280031 0.63 ALDH1A1 (0.49)
SCHEMBL7510962 0.61
SCHEMBL31708953 0.56 F2RL1 (0.33)
SCHEMBL12126327 0.54
SCHEMBL21693512 0.53
Ether SCHEMBL7593160 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376526-B1 FOR HUANS, ANIMALS PFIZER INC. 2002-04-23 US disclosed
EP-0796858-B1 Triazole antifungal agents PFIZER LTD (GB) 2000-11-02 EP disclosed
US-6124325-A Triazole antifungal agents PFIZER INC. (US) 2000-09-26 US disclosed
US-5981560-A 1,2,4-TRIAZOLE FUNGICIDES PFIZER INC. (US) 1999-11-09 US disclosed
EP-0796858-A1 Triazole antifungal agents Pfizer Limited (GB) 1997-09-24 EP disclosed