Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7679712 | 0.91 | SLC10A2 (0.84) | SLC10A2 | |
| Iodide SCHEMBL7679687 | 0.90 | SLC10A2 (0.81) | SLC10A2 | |
| SCHEMBL7852437 | 0.84 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL13320314 | 0.83 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL9961483 | 0.83 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL7673034 | 0.80 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL6711818 | 0.76 | SLC10A2 (0.97) | SLC10A2 | |
| SCHEMBL7850994 | 0.75 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL6711820 | 0.73 | SLC10A2 (0.81) | SLC10A2 | |
| SCHEMBL7850982 | 0.73 | SLC10A2 (1.00) | SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002536440-A | — | — | 2002-10-29 | — | — | JP | claimed |
| EP-1155007-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. Searle LLC (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2000047568-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. SEARLE LLC (US) | 2000-08-17 | — | — | WO | claimed |