SCHEMBL7852437

SCHEMBL7852437

CCCCC1(CCCC)NS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(OC)cc2)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7673034 0.88 SLC10A2 (1.00) SLC10A2
Iodide SCHEMBL7679669 0.84 SLC10A2 (1.00) SLC10A2
SCHEMBL7850994 0.82 SLC10A2 (1.00) SLC10A2
SCHEMBL14904727 0.81 SLC10A2 (1.00) SLC10A2
SCHEMBL6221429 0.81 SLC10A2 (1.00) SLC10A2
SCHEMBL14906446 0.81 SLC10A2 (1.00) SLC10A2
SCHEMBL14904728 0.81 SLC10A2 (1.00) SLC10A2
SCHEMBL30804965 0.81 SLC10A2 (1.00) SLC10A2
SCHEMBL22175203 0.81 SLC10A2 (1.00) SLC10A2
SCHEMBL7670967 0.80 SLC10A2 (1.00) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155007-A2 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES G.D. Searle LLC (US) 2001-11-21 EP disclosed
WO-2000047568-A2 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES G.D. SEARLE LLC (US) 2000-08-17 WO disclosed