Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CCKAR | P32238 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 17/20 | 0.39 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688738 | 0.94 | MEN1 (0.46) | MEN1CCKARKMT2AF10F2 | |
| SCHEMBL7688495 | 0.93 | MEN1 (0.39) | MEN1CCKARKMT2AF10F2 | |
| SCHEMBL6703723 | 0.92 | F10 (0.36) | MEN1CCKARKMT2AF10 | |
| SCHEMBL7086907 | 0.91 | F10 (0.38) | MEN1CCKARKMT2AF10F2 | |
| SCHEMBL6704664 | 0.90 | SAE1 (0.33) | F10 | |
| SCHEMBL7685928 | 0.89 | CNR2 (0.42) | MEN1CCKARKMT2AF10CNR2 | |
| SCHEMBL6705251 | 0.89 | SAE1 (0.34) | — | |
| SCHEMBL6703652 | 0.87 | MEN1 (0.38) | MEN1CCKARKMT2AF10 | |
| SCHEMBL6702286 | 0.87 | MAPT (0.32) | KMT2AF10 | |
| SCHEMBL7679717 | 0.85 | MEN1 (0.40) | MEN1CCKARKMT2AF10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |