Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GPX4 | P36969 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679713 | 0.91 | MEN1 (0.40) | F10MEN1CCKARKMT2ACNR2 | |
| SCHEMBL6703562 | 0.87 | MAPT (0.33) | SCDKMT2ATP53MAPTTRPV4 | |
| SCHEMBL7688738 | 0.85 | MEN1 (0.46) | F10MEN1CCKARKMT2ACNR2 | |
| SCHEMBL6702299 | 0.84 | TRPV4 (0.38) | F10SCDMEN1CCKARKMT2A | |
| SCHEMBL7688495 | 0.84 | MEN1 (0.39) | F10MEN1CCKARKMT2ACNR2 | |
| SCHEMBL6702438 | 0.84 | MAPT (0.38) | MEN1KMT2ATP53MAPT | |
| SCHEMBL6703723 | 0.83 | F10 (0.36) | F10MEN1CCKARKMT2ATP53 | |
| SCHEMBL6704665 | 0.83 | CHRM4 (0.33) | KMT2ATP53MAPT | |
| SCHEMBL7086912 | 0.82 | SCD (0.36) | F10SCDMEN1CCKARKMT2A | |
| SCHEMBL6704664 | 0.81 | SAE1 (0.33) | F10TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |