Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688738 | 0.91 | MEN1 (0.46) | CNR2MEN1CCKARKMT2AF10 | |
| SCHEMBL7682297 | 0.91 | CNR2 (0.40) | CNR2MEN1CCKARKMT2AF10 | |
| SCHEMBL7679713 | 0.89 | MEN1 (0.40) | CNR2MEN1CCKARKMT2AF10 | |
| SCHEMBL7688495 | 0.87 | MEN1 (0.39) | CNR2MEN1CCKARKMT2AF10 | |
| SCHEMBL7685931 | 0.86 | CNR2 (0.41) | CNR2MEN1CCKARKMT2AHDAC1 | |
| SCHEMBL6703652 | 0.84 | MEN1 (0.38) | MEN1CCKARKMT2AF10ALDH1A1 | |
| SCHEMBL6703723 | 0.81 | F10 (0.36) | MEN1CCKARKMT2AF10ALDH1A1 | |
| SCHEMBL7679728 | 0.80 | TP53 (0.36) | KMT2AF10HTTTRPV4 | |
| SCHEMBL6704409 | 0.80 | MAPT (0.32) | MEN1CCKARKMT2AF10ALDH1A1 | |
| SCHEMBL7086907 | 0.80 | F10 (0.38) | CNR2MEN1CCKARKMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |