⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24792709 | 0.79 | KMT2A (0.34) | — | |
| SCHEMBL23457288 | 0.78 | — | — | |
| SCHEMBL332480 | 0.76 | — | — | |
| SCHEMBL14048787 | 0.74 | — | — | |
| SCHEMBL18773241 | 0.73 | MET (0.35) | — | |
| SCHEMBL19159793 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL18529372 | 0.71 | — | — | |
| SCHEMBL3005643 | 0.70 | KMT2A (0.34) | — | |
| SCHEMBL3005642 | 0.70 | KMT2A (0.34) | — | |
| SCHEMBL18949206 | 0.70 | KMT2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917289-A | T-type calcium channel antagonists and uses thereof | 小利兰·斯坦福大学董事会 | 2023-10-20 | — | — | CN | disclosed |
| US-20160153015-A1 | SYNTHESIS METHOD FOR L-HETEROCYCLIC AMINO ACID AND PHARMACEUTICAL COMPOSITION HAVING THEREOF | JILIN ASYMCHEM LABORATORIES CO., LTD (CN) | 2016-06-02 | — | — | US | disclosed |
| CN-103764145-A | Isoxazolines as therapeutic agents | ABBOTT LAB | 2014-04-30 | — | — | CN | disclosed |
| US-6376526-B1 | FOR HUANS, ANIMALS | PFIZER INC. | 2002-04-23 | — | — | US | disclosed |
| EP-0796858-B1 | Triazole antifungal agents | PFIZER LTD (GB) | 2000-11-02 | — | — | EP | disclosed |
| US-6124325-A | Triazole antifungal agents | PFIZER INC. (US) | 2000-09-26 | — | — | US | disclosed |
| US-5981560-A | 1,2,4-TRIAZOLE FUNGICIDES | PFIZER INC. (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0796858-A1 | Triazole antifungal agents | Pfizer Limited (GB) | 1997-09-24 | — | — | EP | disclosed |