SCHEMBL7679743

SCHEMBL7679743

CCCCS(=O)(=O)NC(CC(=O)O)C(=O)Cn1nnc(Cc2c(Cl)cccc2Cl)n1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.37
ITGB3 P05106 3/20 0.33
ITGA2B P08514 3/20 0.33
PPARG P37231 1/20 0.33
TLR7 Q9NYK1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7685555 0.97 CNR2 (0.36) CNR2PPARG
SCHEMBL7682345 0.90 CASP1 (0.40) CNR2
SCHEMBL7677083 0.89 CNR2 (0.36) CNR2
SCHEMBL8171963 0.89 CNR2 (0.36) CNR2
Hydrochloric Acid SCHEMBL7688999 0.88 CNR2 (0.35) CNR2
SCHEMBL7679416 0.86 CNR2 (0.38) CNR2
SCHEMBL7679645 0.86 CNR2 (0.40) CNR2ITGB3ITGA2B
SCHEMBL7680424 0.85 MMP13 (0.45)
SCHEMBL7678024 0.84 CNR2 (0.40) CNR2ITGB3
SCHEMBL7675723 0.83 CASP1 (0.43) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136834-A TETRAZOLE PEPTIDES ONO PHARMACEUTICAL CO., LTD. (JP) 2000-10-24 US claimed
EP-0900791-A1 TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 1999-03-10 EP claimed
US-6376484-B1 FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE ONO PHARMACEUTICAL CO., LTD. (JP) 2002-04-23 US disclosed
US-6136834-A TETRAZOLE PEPTIDES ONO PHARMACEUTICAL CO., LTD. (JP) 2000-10-24 US disclosed
EP-0900791-A1 TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 1999-03-10 EP disclosed