Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 12/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7556361 | 0.87 | CRHR1 (0.60) | CRHR1TDP1 | |
| SCHEMBL7681592 | 0.85 | CRHR1 (0.58) | CRHR1TDP1ABCB1 | |
| SCHEMBL7684158 | 0.79 | CRHR1 (0.55) | CRHR1TDP1 | |
| SCHEMBL226802 | 0.76 | CRHR1 (0.77) | CRHR1TDP1 | |
| SCHEMBL7791101 | 0.75 | CRHR1 (0.48) | CRHR1ABCB1 | |
| SCHEMBL7684145 | 0.74 | CRHR1 (0.54) | CRHR1ABCB1 | |
| SCHEMBL7559415 | 0.73 | CRHR1 (0.70) | CRHR1TDP1 | |
| SCHEMBL7684260 | 0.73 | CRHR1 (0.48) | CRHR1ABCB1 | |
| SCHEMBL7677447 | 0.73 | CRHR1 (0.53) | CRHR1TDP1ABCB1 | |
| SCHEMBL7676298 | 0.73 | CRHR1 (0.48) | CRHR1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362186-B1 | PSYCHOLOGICAL DISORDERS | NEUROGEN CORPORATION | 2002-03-26 | — | — | US | claimed |
| US-6362186-B1 | PSYCHOLOGICAL DISORDERS | NEUROGEN CORPORATION | 2002-03-26 | — | — | US | disclosed |
| US-6147085-A | Aminoalkyl substituted 9H-pyridino[2,3-b] indole and 9H-pyrimidino[4,5-b] indole derivatives | NEUROGEN CORPORATION (US) | 2000-11-14 | — | — | US | disclosed |