SCHEMBL76803

SCHEMBL76803

CCCCOC(=O)/C(C#N)=C(\C)c1ccc(OC)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.43
POLB P06746 3/20 0.43
KMT2A Q03164 3/20 0.43
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
LMNA P02545 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
CYP1A2 P05177 2/20 0.41
TSHR P16473 2/20 0.41
MAPK1 P28482 2/20 0.41
CYP2C19 P33261 2/20 0.41
ESR1 P03372 1/20 0.41
CYP2D6 P10635 1/20 0.41
NR1H2 P55055 1/20 0.41
RNASEL Q05823 1/20 0.41
ALDH1A1 P00352 3/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
PDE4D Q08499 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76804 1.00 HPGD (0.43) HPGDPOLBKMT2AHDAC3HDAC1
SCHEMBL19465674 0.96 HDAC3 (0.43) HPGDPOLBKMT2AHDAC3HDAC1
SCHEMBL15127487 0.91 HTT (0.48) HPGDPOLBKMT2ALMNASMN1; SMN2
SCHEMBL7085242 0.88 ALDH1A1 (0.45) HPGDKMT2ALMNASMN1; SMN2CYP1A2
SCHEMBL12755372 0.88 LMNA (0.42) HPGDLMNASMN1; SMN2CYP1A2TSHR
SCHEMBL1553877 0.88 CYP19A1 (0.50) HPGDPOLBKMT2AHDAC3HDAC1
SCHEMBL1553875 0.88 CYP19A1 (0.50) HPGDPOLBKMT2AHDAC3HDAC1
SCHEMBL9180325 0.88 CYP19A1 (0.50) HPGDPOLBKMT2AHDAC3HDAC1
SCHEMBL15876843 0.86 NR1I2 (0.50) HPGDPOLBKMT2AHDAC3HDAC1
SCHEMBL28141864 0.86 NR1I2 (0.50) HPGDPOLBKMT2AHDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2594 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532595-A1 POLYCARBONATE COMPOSITION CONTAINING COMBINATION OF HYDROXYPHENYL TRIAZINES AND UV ABSORBERS BASF SE (DE) 2025-04-09 EP disclosed
WO-2024150714-A1 PROCESSING STABILIZER, RESIN COMPOSITION, AND ORGANIC MATERIAL STABILIZING METHOD 住友化学株式会社 2024-07-18 WO disclosed
US-12036737-B2 Film areas functionalized by means of 3D printing for finishing workpiece surfaces STRATASYS, INC. (US) 2024-07-16 US disclosed
EP-3245240-B1 COMPOSITION FOR TRANSPARENT MOULDED OBJECTS BASED ON POLYURETHANE COVESTRO DEUTSCHLAND AG (DE) 2024-07-03 EP disclosed
US-12006417-B2 Additive mixture containing a particular sterically hindered amine compound and a heat reflecting interference pigment BASF SE (DE) 2024-06-11 US disclosed
US-20240174839-A1 STABILIZER MIXTURE BASF SE (DE) 2024-05-30 US disclosed
US-20240166672-A1 PHOSPHOROUS ESTER COMPOUND, METHOD FOR PRODUCING SAME AND USE APPLICATION FOR SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-05-23 US disclosed
EP-4371988-A1 PHENOLIC COMPOUND, ORGANIC MATERIAL STABILIZER, RESIN COMPOSITION, AND METHOD FOR STABILIZING ORGANIC MATERIAL Sumitomo Chemical Company, Limited (JP) 2024-05-22 EP disclosed
US-11981793-B2 Use of an ultraviolet radiation absorbing composition as a light stabilizer for a shaped artificial polymer article BASF SE (DE) 2024-05-14 US disclosed
US-20240150099-A1 DEGRADABLE MATERIALS AND PACKAGING MADE FROM SAME MONOSOL, LLC 2024-05-09 US disclosed
US-4532279-A Polyalkylpiperidine esters of aliphatic tetracarboxylic acids CIBA-GEIGY CORPORATION (US) 1985-07-30 US disclosed
US-4513109-A FOR LUBRICATING OILS AND POLYMERS CIBA-GEIGY CORPORATION (US) 1985-04-23 US disclosed
US-4507420-A LUBRICANT OIL ADDITIVES; IMPARTS PHOTOSTABILITY TO POLYMERS CIBA-GEIGY CORPORATION (US) 1985-03-26 US disclosed
US-4419472-A FOR PLASTICS CIBA-GEIGY CORPORATION (US) 1983-12-06 US disclosed
US-4325989-A ULTRAVIOLET RADIATION ABSORBER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-04-20 US disclosed
US-4263408-A Process for the production of molded foams BAYER AKTIENGESELLSCHAFT (DE) 1981-04-21 US disclosed
US-4123418-A BIS-(U8I8I8L8L-PENTAMETHY TETRAMETHYL-4-PIPERIDYL)-SUBERATE CIBA-GEIGY CORPORATION (US) 1978-10-31 US disclosed
US-4110304-A STERICALLY HINDERED CYCLIC AMINE CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed
US-4061631-A STABILIZER CIBA-GEIGY CORPORATION (US) 1977-12-06 US disclosed
US-3943098-A 1-Aza-4-thiacyclohexane-4,4-dioxide derivatives and their use as agents protecting against light rays CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed