Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 8/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684958 | 0.69 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL7681117 | 0.68 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL13097696 | 0.66 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL7676535 | 0.65 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL7680517 | 0.65 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL840544 | 0.63 | ALDH1A1 (0.52) | CRHR1 | |
| SCHEMBL24352667 | 0.62 | MCL1 (0.39) | CRHR1 | |
| SCHEMBL7681102 | 0.62 | POLB (0.36) | CRHR1 | |
| Hydrochloric Acid SCHEMBL6981827 | 0.62 | GAA (0.50) | CRHR1 | |
| SCHEMBL16693977 | 0.61 | KDM4E (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | disclosed |
| US-6107301-A | PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995010506-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-04-20 | — | — | WO | disclosed |