Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 12/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524914 | 0.84 | EGFR (0.46) | EGFRNR1I2ADRA2AADORA3TBXA2R | |
| SCHEMBL11421197 | 0.69 | NR1I2 (0.74) | EGFRNR1I2ADRA2AADORA3TBXA2R | |
| SCHEMBL11812210 | 0.68 | NR1I2 (0.58) | EGFRNR1I2ADRA2AADORA3TBXA2R | |
| SCHEMBL3521859 | 0.68 | CASR (0.53) | EGFRNR1I2ADRA2AADORA3TBXA2R | |
| SCHEMBL3522604 | 0.67 | NR1I2 (0.62) | EGFRNR1I2ADRA2AADORA3TBXA2R | |
| Proquazone SCHEMBL25341 | 0.65 | NR1I2 (1.00) | EGFRNR1I2ADRA2AADORA3TBXA2R | |
| SCHEMBL11161844 | 0.65 | CASR (0.64) | EGFRNR1I2ADRA2AADORA3TBXA2R | |
| SCHEMBL7680445 | 0.65 | NR1I2 (0.72) | EGFRNR1I2ADRA2AADORA3TBXA2R | |
| Proquazone SCHEMBL2931942 | 0.65 | NR1I2 (0.97) | EGFRNR1I2ADRA2AADORA3TBXA2R | |
| SCHEMBL11601877 | 0.65 | CASR (0.67) | EGFRNR1I2ADRA2AADORA3TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465472-B1 | SUCH AS 1-(2-DIETHYLAMINOETHYL)-6,7-METHYLENEDIOXY-4-(3,4-METHYLENE -DIOXYPHENYL)QUINAZOLIN-2(1H)-ONE; AMPA IONOTROPIC RECEPTOR ANTAGONISTS; ANTICONVULSANTS, COGNITIVE ENHANCERS, PREVENTION OF NEURODEGENERATION | EURO-CELTIQUE S.A. (LU) | 2002-10-15 | — | — | US | disclosed |