Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684958 | 0.86 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL7678511 | 0.84 | CRHR1 (0.41) | CRHR1ALDH1A1 | |
| SCHEMBL7680517 | 0.80 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL7684542 | 0.79 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL7681117 | 0.75 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL7678441 | 0.67 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL7676535 | 0.66 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL23903368 | 0.66 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL1638416 | 0.65 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL7680362 | 0.65 | CRHR1 (0.36) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | disclosed |
| US-6107301-A | PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-08-22 | — | — | US | disclosed |