Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.66 |
| ▸ | F12 | P00748 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679435 | 0.85 | F2 (0.60) | F2F12CA12CA9CA2 | |
| SCHEMBL7679254 | 0.80 | F2 (0.68) | F2F12CA12CA9CA2 | |
| SCHEMBL7679864 | 0.80 | F2 (1.00) | F2F12CA12CA9CA2 | |
| SCHEMBL7675773 | 0.80 | F2 (0.59) | F2F12CA12CA9CA2 | |
| SCHEMBL7675741 | 0.78 | F2 (0.60) | F2F12CA12CA9MAPT | |
| SCHEMBL7679485 | 0.78 | F2 (0.69) | F2F12CA12CA9CA2 | |
| SCHEMBL18752290 | 0.77 | F2 (0.73) | F2F12CA12CA9CA2 | |
| SCHEMBL18752376 | 0.76 | F2 (0.76) | F2F12CA12CA9CA2 | |
| SCHEMBL18607531 | 0.76 | F2 (0.79) | F2F12CA12CA9CA2 | |
| SCHEMBL7679378 | 0.76 | CA12 (0.79) | F2F12CA12CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |