Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | VCP | P55072 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783840 | 0.90 | LMNA (0.69) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10808572 | 0.84 | MEN1 (0.82) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3607683 | 0.84 | MEN1 (0.66) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6376187 | 0.79 | MEN1 (0.77) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8823146 | 0.78 | ALDH1A1 (1.00) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6227272 | 0.78 | MAPT (0.81) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8172368 | 0.77 | CA12 (0.64) | MEN1KMT2AMAPTLMNAADORA3 | |
| SCHEMBL3615040 | 0.77 | MEN1 (0.57) | ALOX5MEN1KMT2AMAPTVCP | |
| SCHEMBL23604714 | 0.76 | ABL1 (0.74) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4555000 | 0.76 | MAPT (0.72) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410533-B1 | THERAPY FOR BACTERIA INFECTIONS | GENZYME CORPORATION | 2002-06-25 | — | — | US | disclosed |