Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | MAX | P61244 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660146 | 0.89 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7681577 | 0.88 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7569031 | 0.82 | PTPN7 (0.54) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7660134 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7639391 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7642326 | 0.74 | TRPV1 (0.47) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6816290 | 0.74 | LMNA (0.65) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7568351 | 0.73 | MAPT (0.67) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1927873 | 0.72 | GAA (0.50) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL6815190 | 0.72 | QPCT (0.58) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407123-B1 | VIRICIDES FOR TREATMENT OF HUMAN CYTOMEGALO, EPSTEIN-BARR, VARICELLA-ZOSTER AND KAPOSI*S HERPES VIRAL INFECTIONS | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |