Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024749 | 0.77 | KMT2A (0.46) | MAPTKMT2A | |
| SCHEMBL1893396 | 0.73 | PARP1 (0.44) | MAPT | |
| SCHEMBL753675 | 0.68 | ALDH1A1 (0.48) | MAPTKMT2A | |
| SCHEMBL4372772 | 0.68 | PBRM1 (0.37) | MAPTKMT2A | |
| SCHEMBL1948316 | 0.67 | F2 (0.33) | KMT2A | |
| SCHEMBL6160784 | 0.64 | GAA (0.47) | — | |
| SCHEMBL10412258 | 0.64 | HSP90AB1 (0.39) | MAPTKMT2A | |
| SCHEMBL1100763 | 0.64 | GAA (0.48) | — | |
| SCHEMBL1098615 | 0.64 | TSHR (0.50) | MAPTKMT2A | |
| SCHEMBL12521035 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462034-B1 | MULTIBINDING COMPOUNDS CONTAINING A SYMETRICAL DIAMINOTETRA-ETHERDODECANE RING WITH TWO SECONDARY AMIDE AND ADDITIONAL SUBSTITUENTS; VOLTAGE GATED SODIUM CHANNEL MODULATORS; LONG DURATION | THERAVANCE, INC. | 2002-10-08 | — | — | US | disclosed |