Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 9/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | F12 | P00748 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676641 | 0.89 | F12 (0.50) | MAPTGAACA12CA9MAOB | |
| SCHEMBL18752250 | 0.89 | CA12 (0.56) | MAPTGAACA12CA9MAOB | |
| SCHEMBL18752252 | 0.87 | CA12 (0.57) | MAPTGAACA12CA9MAOB | |
| SCHEMBL7682500 | 0.86 | POLB (0.60) | MAPTGAACA12CA9MAOB | |
| SCHEMBL7675741 | 0.86 | F2 (0.60) | MAPTGAACA12CA9MAOB | |
| SCHEMBL7681261 | 0.85 | POLB (0.55) | MAPTGAACA12CA9MAOB | |
| SCHEMBL27951961 | 0.77 | CA12 (0.74) | MAPTGAACA12CA9MAOB | |
| SCHEMBL30595105 | 0.77 | CA12 (0.69) | MAPTGAACA12CA9MAOB | |
| SCHEMBL7672880 | 0.77 | CA12 (0.69) | MAPTGAACA12CA9MAOB | |
| SCHEMBL18752273 | 0.76 | MEN1 (0.56) | CA12CA9MAOBPOLBF12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |