Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682533 | 0.88 | MEN1 (0.60) | POLBMAOAMAOBMEN1KMT2A | |
| SCHEMBL7682335 | 0.86 | MAPT (0.58) | POLBMAOAMAOBMEN1KMT2A | |
| SCHEMBL18752252 | 0.85 | CA12 (0.57) | POLBMAOAMAOBMEN1KMT2A | |
| SCHEMBL18752250 | 0.85 | CA12 (0.56) | POLBMAOAMAOBKMT2AKDM4E | |
| SCHEMBL7675741 | 0.84 | F2 (0.60) | POLBMAOAMAOBMAPTCA12 | |
| SCHEMBL7681261 | 0.82 | POLB (0.55) | POLBMAOAMAOBKMT2AKDM4E | |
| SCHEMBL20582728 | 0.79 | POLB (0.80) | POLBMAOAMAOBMEN1KMT2A | |
| SCHEMBL6897218 | 0.77 | POLB (0.61) | POLBMAOAMAOBMEN1KMT2A | |
| SCHEMBL18752273 | 0.76 | MEN1 (0.56) | POLBMAOBMEN1KMT2AATM | |
| SCHEMBL7679254 | 0.75 | F2 (0.68) | POLBMEN1KMT2AATMCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |