Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 5/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686588 | 0.96 | F10 (0.36) | F10MDM2ECE1KDM4EALDH1A1 | |
| SCHEMBL6702793 | 0.90 | MAPT (0.37) | KDM4EALDH1A1HPGDNPSR1RXFP1 | |
| SCHEMBL6703652 | 0.89 | MEN1 (0.38) | F10MDM2KDM4EALDH1A1HPGD | |
| SCHEMBL7684403 | 0.89 | F10 (0.35) | F10MDM2KDM4EALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL7682405 | 0.87 | ATM (0.35) | ATMECE1KDM4EALDH1A1HPGD | |
| SCHEMBL7679774 | 0.85 | SAE1 (0.35) | F10MEN1KMT2ACCKARCHRM4 | |
| SCHEMBL6702438 | 0.85 | MAPT (0.38) | KDM4EALDH1A1HPGDNPSR1MEN1 | |
| SCHEMBL6699872 | 0.84 | PTGDR2 (0.36) | KDM4EALDH1A1HPGDNPSR1RXFP1 | |
| SCHEMBL6703723 | 0.84 | F10 (0.36) | F10MDM2ALDH1A1RXFP1MEN1 | |
| SCHEMBL6704665 | 0.84 | CHRM4 (0.33) | KDM4EALDH1A1HPGDNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |