Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686588 | 0.89 | F10 (0.36) | PTGDR2KMT2AMEN1CCKARCHRM4 | |
| SCHEMBL6702793 | 0.88 | MAPT (0.37) | KMT2AMEN1TP53 | |
| SCHEMBL6702895 | 0.87 | CHRM4 (0.35) | SAE1UBA2ROCK2CHRM4TP53 | |
| Trifluoroacetic Acid SCHEMBL7682402 | 0.85 | ATM (0.36) | KMT2AMEN1CCKARCHRM4TP53 | |
| SCHEMBL7679779 | 0.85 | TRPV4 (0.37) | SAE1UBA2PTGDR2KMT2APOLB | |
| SCHEMBL6699872 | 0.85 | PTGDR2 (0.36) | PTGDR2KMT2APOLBMEN1CHRM4 | |
| SCHEMBL7688738 | 0.84 | MEN1 (0.46) | KMT2AMEN1CCKARF10 | |
| SCHEMBL7682297 | 0.84 | CNR2 (0.40) | SAE1UBA2PTGDR2KMT2AMEN1 | |
| SCHEMBL6704665 | 0.83 | CHRM4 (0.33) | SAE1UBA2KMT2AROCK2CHRM4 | |
| SCHEMBL6702438 | 0.83 | MAPT (0.38) | KMT2AMEN1CHRM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |