Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.31 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704664 | 0.94 | SAE1 (0.33) | CHRM4MAPTSAE1ROCK2ALDH1A1 | |
| SCHEMBL6702438 | 0.92 | MAPT (0.38) | CHRM4MAPTALDH1A1KDM4ETSHR | |
| SCHEMBL6702895 | 0.89 | CHRM4 (0.35) | CHRM4MAPTSAE1UBA2ROCK2 | |
| SCHEMBL6700553 | 0.89 | CHRM4 (0.33) | CHRM4MAPTSAE1UBA2ROCK2 | |
| SCHEMBL7686588 | 0.87 | F10 (0.36) | CHRM4MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL6702793 | 0.86 | MAPT (0.37) | MAPTALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL7684403 | 0.86 | F10 (0.35) | CHRM4MAPTSAE1UBA2ALDH1A1 | |
| SCHEMBL6703723 | 0.86 | F10 (0.36) | MAPTALDH1A1KMT2ATP53LMNA | |
| SCHEMBL6704668 | 0.84 | TRPV4 (0.34) | CHRM4MAPTSAE1UBA2ROCK2 | |
| SCHEMBL7679713 | 0.84 | MEN1 (0.40) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |