Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | PLTP | P55058 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7682405 | 0.91 | ATM (0.35) | TRPV4MAPTECE1PLTPALDH1A1 | |
| SCHEMBL7686591 | 0.90 | TRPV4 (0.36) | TRPV4MAPTECE1PLTPALDH1A1 | |
| SCHEMBL7684406 | 0.89 | MAPT (0.34) | TRPV4MAPTECE1PLTPALDH1A1 | |
| SCHEMBL6702441 | 0.87 | MAPT (0.39) | TRPV4MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL6703725 | 0.86 | MAPT (0.34) | TRPV4MAPTECE1PLTPALDH1A1 | |
| SCHEMBL226080 | 0.85 | TRPV4 (0.32) | TRPV4PLTPTP53 | |
| SCHEMBL7682217 | 0.85 | TRPV4 (0.38) | TRPV4MAPTECE1PLTPALDH1A1 | |
| SCHEMBL6704668 | 0.85 | TRPV4 (0.34) | TRPV4MAPTECE1PLTPALDH1A1 | |
| SCHEMBL6702797 | 0.84 | GAA (0.39) | TRPV4MAPTECE1ALDH1A1HPGD | |
| SCHEMBL6703653 | 0.84 | MEN1 (0.37) | TRPV4MAPTECE1PLTPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |