Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700319 | 1.00 | KMT2A (0.36) | KMT2AL3MBTL1MAPTNPSR1POLB | |
| SCHEMBL6695414 | 0.84 | KMT2A (0.36) | KMT2AL3MBTL1MAPTNPSR1POLB | |
| SCHEMBL6698365 | 0.80 | KMT2A (0.41) | KMT2AL3MBTL1NPSR1MEN1MAPK1 | |
| SCHEMBL6693830 | 0.78 | KMT2A (0.39) | KMT2AL3MBTL1NPSR1MEN1MAPK1 | |
| SCHEMBL7230182 | 0.77 | POLB (0.34) | KMT2AMAPTNPSR1POLBTDP1 | |
| SCHEMBL7232763 | 0.77 | POLB (0.34) | KMT2AMAPTNPSR1POLBTDP1 | |
| SCHEMBL6693489 | 0.77 | KMT2A (0.35) | KMT2AL3MBTL1MAPTNPSR1POLB | |
| SCHEMBL6704197 | 0.76 | KMT2A (0.42) | KMT2AL3MBTL1 | |
| SCHEMBL6698778 | 0.76 | KMT2A (0.37) | KMT2AL3MBTL1NPSR1MEN1MAPK1 | |
| SCHEMBL6697245 | 0.76 | SIGMAR1 (0.40) | KMT2AL3MBTL1MAPTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455571-B1 | ESPECIALLY, INFLUENZA NEURAMINIDASE. | ABBOTT LABORATORIES | 2002-09-24 | — | — | US | disclosed |