Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 8/20 | 0.37 |
| ▸ | CTSL | P07711 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025882 | 0.92 | SIGMAR1 (0.42) | SIGMAR1CTSKCTSLCTSBCTSS | |
| SCHEMBL7166857 | 0.92 | SIGMAR1 (0.42) | SIGMAR1CTSKCTSLCTSBCTSS | |
| SCHEMBL7684372 | 0.86 | SIGMAR1 (0.42) | SIGMAR1CTSKCTSLKMT2ACTSB | |
| SCHEMBL6697716 | 0.86 | SIGMAR1 (0.42) | SIGMAR1CTSKCTSLKMT2ACTSB | |
| SCHEMBL6704197 | 0.84 | KMT2A (0.42) | CTSKCTSLKMT2ACTSBCTSS | |
| SCHEMBL6702372 | 0.82 | SIGMAR1 (0.43) | SIGMAR1CTSKCTSLKMT2ACTSB | |
| SCHEMBL6698365 | 0.81 | KMT2A (0.41) | KMT2AL3MBTL1MEN1MAPK1NPSR1 | |
| SCHEMBL6693830 | 0.80 | KMT2A (0.39) | KMT2AL3MBTL1MEN1MAPK1NPSR1 | |
| SCHEMBL6697678 | 0.79 | SIGMAR1 (0.43) | SIGMAR1CTSKCTSLKMT2ACTSB | |
| SCHEMBL6702380 | 0.79 | SIGMAR1 (0.43) | SIGMAR1CTSKCTSLKMT2ACTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831096-B2 | Effective against both A and B forms of influenza; oral bioavailability | ABBOTT LABORATORIES | 2004-12-14 | — | — | US | disclosed |
| US-20040097471-A1 | Inhibitors of neuraminidases | ABBVIE INC. | 2004-05-20 | — | — | US | disclosed |
| US-6455571-B1 | ESPECIALLY, INFLUENZA NEURAMINIDASE. | ABBOTT LABORATORIES | 2002-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097471-A1 | Inhibitors of neuraminidases | NEU1, NEU2, NEU4 | SIGMAR1 3896/4885CTSK 239/4885CTSL 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.