Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679550 | 0.90 | MAPT (0.62) | ABCB11CCR2 | |
| SCHEMBL7691746 | 0.85 | ABCB11 (1.00) | ABCB11CCR2 | |
| SCHEMBL7679941 | 0.84 | ABCB11 (0.78) | ABCB11CCR2 | |
| SCHEMBL7505898 | 0.82 | ABCB11 (0.70) | ABCB11CCR2 | |
| SCHEMBL7680085 | 0.81 | ABCB11 (0.73) | ABCB11CCR2 | |
| SCHEMBL7680923 | 0.81 | ABCB11 (0.65) | ABCB11CCR2 | |
| SCHEMBL7682986 | 0.80 | ABCB11 (0.71) | ABCB11CCR2 | |
| SCHEMBL7682792 | 0.77 | ABCB11 (0.67) | ABCB11CCR2 | |
| SCHEMBL7511032 | 0.76 | MAPT (0.59) | ABCB11CCR2 | |
| SCHEMBL6300956 | 0.76 | CCR2 (1.00) | ABCB11CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479527-B1 | Bicyclic pyrrole derivatives as MCP-1 inhibitors | ASTRAZENECA UK LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1056451-A1 | BICYCLIC PYRROLE DERIVATIVES AS MCP-1 INHIBITORS | AstraZeneca UK Limited (GB) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999040914-A1 | BICYCLIC PYRROLE DERIVATIVES AS MCP-1 INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |