Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | PSMB10 | P40306 | 7/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 9/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 8/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 8/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 7/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 6/20 | 0.45 |
| ▸ | YAP1 | P46937 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5832989 | 1.00 | MME (0.49) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL5832987 | 1.00 | MME (0.49) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL5833255 | 0.88 | MME (0.48) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL5833253 | 0.88 | MME (0.48) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL5833955 | 0.86 | PSMB1 (0.51) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL5833960 | 0.86 | PSMB1 (0.51) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL7364989 | 0.77 | MME (0.56) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL7866955 | 0.77 | CAPN1 (0.50) | MMEACECPA1ACE2PSMB10 | |
| SCHEMBL8692584 | 0.77 | ITGB3 (0.51) | MMEACECPA1ACE2ITGB3 | |
| SCHEMBL8696145 | 0.77 | ITGB3 (0.51) | MMEACECPA1ACE2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469038-B1 | CALCIUM CHANNEL BLOCKERS THAT CAN BLOCK N-TYPE CALCIUM CHANNELS AND CAN BE USED TO TREAT STROKE, PAIN, CEREBRAL ISCHEMIA, HEAD TRAUMA, ASTHMA, AMYOTROPIC LATERAL SCLEROSIS, AND EPILEPSY | WARNER-LAMBERT COMPANY | 2002-10-22 | — | — | US | disclosed |