Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821897 | 0.89 | ACP3 (0.53) | ACP3CNR2PPARGPOLQAKR1C3 | |
| SCHEMBL6685785 | 0.87 | ACP3 (0.45) | ACP3CNR2PPARGPOLQAKR1C3 | |
| SCHEMBL7471669 | 0.86 | ACP3 (0.44) | ACP3CNR2PPARGCACNA2D1CACNA1B | |
| SCHEMBL8917002 | 0.82 | ALDH1A1 (0.44) | ACP3CNR2PPARGCACNA1CLMNA | |
| SCHEMBL29129004 | 0.80 | ACP3 (0.47) | ACP3CNR2CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL16371385 | 0.79 | CNR2 (0.50) | ACP3CNR2POLQAKR1C3AKR1C2 | |
| SCHEMBL7680267 | 0.79 | DPP4 (0.41) | PPARGPOLQAKR1C3AKR1C2 | |
| SCHEMBL194437 | 0.79 | AKR1C3 (0.52) | ACP3CNR2PPARGPOLQAKR1C3 | |
| SCHEMBL30428161 | 0.79 | AKR1C3 (0.52) | ACP3CNR2PPARGPOLQAKR1C3 | |
| SCHEMBL3130946 | 0.78 | ACP3 (0.53) | ACP3CNR2PPARGPOLQAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |