SCHEMBL8206326

SCHEMBL8206326

NNc1cc(OC2CCCC2)c(Cl)cc1F

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 12/20 0.46
CSNK2A1 P68400 2/20 0.46
PPOX P50336 2/20 0.44
PDE4D Q08499 2/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7683050 0.83 CSNK2A1 (0.49) SCN9ACSNK2A1PPOXNPC1RAB9A
Hydrochloric Acid SCHEMBL8369025 0.81 CSNK2A1 (0.50) SCN9ACSNK2A1PPOXNPC1RAB9A
SCHEMBL8088011 0.81 SCN9A (0.48) SCN9ACSNK2A1PPOXNPC1RAB9A
SCHEMBL7931893 0.78 SCN9A (0.52) SCN9APPOXPDE4DPDE4APDE4B
SCHEMBL8083764 0.77 SCN9A (0.54) SCN9APPOXPDE4DPDE4APDE4B
SCHEMBL8599165 0.76 CSNK2A1 (0.41) SCN9ACSNK2A1PPOXNPC1
SCHEMBL8191955 0.74 SCN9A (0.46) SCN9APPOXPDE4DPDE4APDE4B
SCHEMBL8760718 0.74 SCN9A (0.46) SCN9ACSNK2A1PPOXPDE4DPDE4A
SCHEMBL10348879 0.74 MAPT (0.38) NPC1RAB9ASMN1; SMN2
SCHEMBL7922423 0.74 SCN9A (0.48) SCN9APPOXPDE4DPDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006105-A1 Benzene derivatives SAGAMI CHEMICAL RESEARCH CENTER (JP) 2000-06-07 EP disclosed
US-5464811-A Benzene derivatives substituted with heterocyclic ring and herbicides containing same as active ingredients SAGAMI CHEMICAL RESEARCH CENTER (JP) 1995-11-07 US disclosed
US-5424277-A An N-substituted-3,4,5,6-tetrahydrophthalimide derivative characterized by having a cycloalkoxy group at the 5-position of the phenyl ring on the nitrogen SAGAMI CHEMICAL RESEARCH CENTER (JP) 1995-06-13 US disclosed
EP-0493606-A1 HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-07-08 EP disclosed