Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686930 | 0.82 | ALOX15 (0.50) | ADORA2AADORA1GAAMAPTALOX15 | |
| SCHEMBL4423266 | 0.78 | ADORA2A (0.55) | ADORA2AADORA1GAAMAPTALOX15 | |
| SCHEMBL24109885 | 0.73 | MAP2K1 (0.34) | — | |
| SCHEMBL7683273 | 0.72 | ADORA2A (0.59) | ADORA2AADORA1MAPTALOX15TSHR | |
| SCHEMBL7685234 | 0.71 | ALOX15 (0.56) | ADORA2AADORA1GAAMAPTALOX15 | |
| SCHEMBL6124100 | 0.71 | CYP19A1 (0.77) | GAAMAPTTSHRHSD17B10KMT2A | |
| SCHEMBL21954834 | 0.70 | MAPT (0.57) | GAAMAPTKMT2AMAP1LC3BMEN1 | |
| SCHEMBL7689646 | 0.69 | HSD17B10 (0.50) | ADORA2AMAPTALOX15TSHRHSD17B10 | |
| SCHEMBL449180 | 0.68 | MAPT (0.82) | GAAMAPTKMT2AMAP1LC3BMEN1 | |
| SCHEMBL5386997 | 0.67 | MAPT (0.59) | GAAMAPTTSHRHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |