Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685234 | 0.82 | ALOX15 (0.56) | HSD17B10ALOX15TSHRLMNARAB9A | |
| SCHEMBL7686930 | 0.75 | ALOX15 (0.50) | HSD17B10ALOX15TSHRLMNARAB9A | |
| Hydrochloric Acid SCHEMBL7685613 | 0.73 | HPGD (0.42) | HSD17B10ALOX15TSHRLMNARAB9A | |
| Hydrochloric Acid SCHEMBL7685612 | 0.73 | HPGD (0.42) | HSD17B10ALOX15TSHRLMNARAB9A | |
| SCHEMBL7683107 | 0.69 | ADORA2A (0.49) | HSD17B10ALOX15TSHRLMNARAB9A | |
| SCHEMBL2016019 | 0.67 | LMNA (0.80) | HSD17B10ALOX15TSHRLMNARAB9A | |
| SCHEMBL7687667 | 0.67 | CSNK2A2 (0.44) | HSD17B10ALOX15TSHRLMNARAB9A | |
| Hydrochloric Acid SCHEMBL27549201 | 0.67 | HSD17B10 (0.39) | HSD17B10ALOX15TSHRLMNARAB9A | |
| SCHEMBL7680997 | 0.67 | HTR2C (0.41) | HSD17B10ALOX15TSHRLMNARAB9A | |
| SCHEMBL16217099 | 0.66 | ALOX15 (0.83) | HSD17B10ALOX15TSHRLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |